The 36-year-old American came from a set and break down to defeat Australia's Ashleigh Barty 3-6, 6-3, 6-4.
There also is a message she wanted to send about self-worth and feeling powerful as she returned to Grand Slam action with a first-round victory at Roland Garros on Tuesday, about nine months after giving birth to a daughter.
"This is my first Grand Slam back and I want to the best that I can".
Serena Williams is officially back!
Williams took the second 6-4 to secure her place in the second round.
Serena recently admitted that she nearly died delivering Olympia as she had to undergo an emergency caesarean section but experienced life-threatening complications, which resulted in surgery to prevent blood clots travelling to her lungs.
Netflix throws serious shade at Roseanne after her show cancellation
Tuesday morning, Barr posted on Twitter about Valerie Jarrett , a former aide to President Barack Obama . Barr had earlier apologized to members of the cast and crew, but the tweet was deleted.
So it proved just over an hour later as Serena was roaring again and holding her arms aloft in triumph after setting up a third round showdown with Germany's 11th seed Julia Goerges.
"Sometimes that is easier said than done, but that is how I want to go about this match". She won match point after Pliskova hit the top of the net on a return.
However, despite her health battles, the 23-time Grand Slam victor hasn't been put off having any more children. The 22-year-old Ashleigh Barty, the world No.17, was not here to make up the numbers but once "Serena came out", it was increasingly hard to see her win. I can show Olympia that I struggled, but now I'm happy with who I am and what I am and what I look like... "I really try to put her first in my life".
"That's what Serena does to you", said Alicia Molik, the Australian Fed Cup captain, who was watching from Barty's player box.
Laughing as she made reference to the fictional nation in sub-Saharan Africa, which is home to superhero Black Panther from Marvel Comics, Williams told reporters: "I feel like a warrior in it, like a warrior princess, a queen from Wakanda maybe".
"I hope now we can wear leggings alone!"
But Williams drew on her unrivalled fighting qualities - and energy reserves some doubted she still possesses at nearly 37 and eight months into motherhood - to stave off Australia's 17th seed after one hour and 46 minutes.