"A vehicle did not respect the right of way and hit him", the tweet read.
Local daily La Nuova Sardegna said Clooney's injuries weren't serious, but that he was taken to the John Paul II hospital emergency room.
George Clooney "smashed in to a windscreen" when his scooter collided with a vehicle in Sardinia.
A fire extinguisher can be seen on the road but no people from the accident were involved.
HuffPost UK has contacted George's representatives for comment.
This is a developing story and will be updated when more information becomes available.
Italy is an important place for Amal and George.
We have to learn to suffer, says Brazil's Neymar
In Brazil's group stage game against Serbia, when he was tackled, that's where his rolling in the World Cup began. With Portugal and Argentina leaving Russian Federation in the round of 16, the award is open for a new victor .
Police told NBC News that the accident happened around 8:15 a.m. local time when a vehicle did not obey the right of way and collided with Clooney at an intersection.
The stunning abode features two swimming pools, a tennis court and an incredibly colourful landscape.
Clooney has a home on Lake Como on the Italian mainland.
In April, the legendary thespian announced he was cutting down his acting role in the Hulu production so he could focus on directing.
Clooney, 57, plays US Air Force commander Scheisskopf in the World War Two Channel 4 drama, based on Joseph Heller's classic novel.
Hugh Laurie also stars as Major de Coverley for the series which has a release date of 2019.