The Reds remain unbeaten this season and have won each of their last nine league games, whereas City have lost three of their last five outings - as many defeats as they suffered in their previous 70.
Fabinho will need to be on his case from minute one because if his influence is felt on the game, it could prove costly for Liverpool. It is because the pressure is greater, especially with the home team aiming to close down a seven-point deficit.
I can't look past City's left-back issue and the option of Liverpool playing Salah, the league's most risky attacker, on that side.
MANCHESTER, Jan 2 ― "I start to read and then I start to think "Liverpool and Juergen Klopp" and I can not focus", said Manchester City manager Pep Guardiola last month, admitting Liverpool's charge to depose the Premier League champions has been in his head for some time.
The reverse fixture between these sides was a terrible goalless draw - no Premier League game in 2018 produced fewer shots - but this one should be considerably more lively.
"It's a massive game, of course it is, but Tottenham will be looking forward to capitalise as well because we both play each other so both of us can't pick up full points".
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With the game nearly a must-win for City in some quarters, the Reds hold all the advantage going in to the tie.
Manchester City returned to winning ways last weekend thanks to a 3-1 win against Southampton to make amends for successive losses to Crystal Palace and Leicester City. They thrashed Arsenal 5-1 in their last outing and Guardiola claims City are the underdogs.
Said the 24-year-old: "If we can play the way we know we can play, we can beat anyone".
However, former Liverpool attacker Raheem Sterling, who was a star of City's own record-breaking side that finished last season with 100 points and 106 goals, warned that his side are confident of beating the Reds. They are at the moment the best team in Europe, in the consistency, the way they control the details in their game.
The Dutch worldwide has already played a key role behind Liverpool's defensive solidity so far this campaign and his physical dominance coupled with his imposing presence in the backline can be intimidating for any attacker.
"I know today nobody trusts us, nobody makes one coin for us, but it is what it is".
'There's no denying it is a huge game for both clubs. "They're unsafe, I mean it".