Federer and Bencic previous year defeated the same German pair of Zverev and Kerber in the final.
However, there was a consolation win for Australia taking the mixed doubles 4-0 4-3 (1).
This year's Hopman Cup had record attendance and also featured the never-before-seen matchup between 37-year-old GOAT's Federer and Serena Williams in another mixed doubles match.
Roger Federer geared up for his Australian Open title defence in convincing fashion, guiding Switzerland to a 2-1 triumph over Germany on Saturday for their fourth Hopman Cup crown.
The world No 3 will be aiming for a third successive Australian Open after looking in impressive touch after claiming a second Hopman Cup.
It was the prefect preparation for the Australian Open as Roger Federer teamed up with Belinda Bencic to help Switzerland defend its Hopman Cup title in Perth.
"It is going to be very exciting and I am hoping it is going to be as exciting as a year ago but just going the other way".
They will attempt to avenge their 2-1 defeat by the Swiss in 2018 and secure a first trophy in the mixed team competition for Germany since 1995.
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"We really wanted to win as a team", Zverev said.
Smashing their way through the first set 4-0, Federer and Bencic looked like they would breeze past the Germans.
However, this may well be the last Hopman Cup, which is scheduled to be displaced by the new ATP Cup which will overlap with the event from next year.
Kerber managed with a 6:4, 7:6 (8:6) how twelve months ago the balance in the duel with Bencic, who is now number 18 in the world rankings. But Federer and Bencic hit back in the second to ensure a tie.
After the match, Federer said his aim for the game was to win points from serve volleys and that worked out for him.
"We will remember for the Rest of our lives this week, especially at this last ball change", said Zverev, and known how much he and Kerber were eager to win the title this time.
"I'm very happy. That was always the goal to get to the final", Federer said.